T Cell Recognition of Distinct Peptide:I-A Conformers in Murine Experimental Autoimmune Encephalomyelitis
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چکیده
منابع مشابه
T cell recognition of distinct peptide:I-Au conformers in murine experimental autoimmune encephalomyelitis.
We have used T cells bearing TCRs that are closely related in sequence as probes to detect conformational variants of peptide-MHC complexes in murine experimental autoimmune encephalomyelitis in H-2(u) mice. The N-terminal epitope of myelin basic protein (MBP) is immunodominant in this model. Our studies have primarily focused on T cell recognition of a position 4 analog of this peptide (MBP1-9...
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